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Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines

BACKGROUND: Epigenetic aberrations and a CpG island methylator phenotype have been shown to be associated with poor outcomes in children with neuroblastoma (NB). Seven cancer related genes (THBS-1, CASP8, HIN-1, TIG-1, BLU, SPARC, and HIC-1) that have been shown to have epigenetic changes in adult c...

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Detalhes bibliográficos
Main Authors: Yang, Qiwei, Tian, Yufeng, Ostler, Kelly R, Chlenski, Alexandre, Guerrero, Lisa J, Salwen, Helen R, Godley, Lucy A, Cohn, Susan L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897803/
https://ncbi.nlm.nih.gov/pubmed/20546602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-286
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