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Using a conformation-dependent stereochemical library improves crystallographic refinement of proteins

The major macromolecular crystallographic refinement packages restrain models to ideal geometry targets defined as single values that are independent of molecular conformation. However, ultrahigh-resolution X-ray models of proteins are not consistent with this concept of ideality and have been used...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tronrud, Dale E., Berkholz, Donald S., Karplus, P. Andrew
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: International Union of Crystallography 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897700/
https://ncbi.nlm.nih.gov/pubmed/20606264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444910019207
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