Impaired Replication Capacity of Acute/Early Viruses in Persons Who Become HIV Controllers

Human immunodeficiency virus type 1 (HIV-1) controllers maintain viremia at <2,000 RNA copies/ml without antiretroviral therapy. Viruses from controllers with chronic infection were shown to exhibit impaired replication capacities, in part associated with escape mutations from cytotoxic-T-lymphoc...

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Detalhes bibliográficos
Main Authors: Miura, Toshiyuki, Brumme, Zabrina L., Brockman, Mark A., Rosato, Pamela, Sela, Jennifer, Brumme, Chanson J., Pereyra, Florencia, Kaufmann, Daniel E., Trocha, Alicja, Block, Brian L., Daar, Eric S., Connick, Elizabeth, Jessen, Heiko, Kelleher, Anthony D., Rosenberg, Eric, Markowitz, Martin, Schafer, Kim, Vaida, Florin, Iwamoto, Aikichi, Little, Susan, Walker, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897600/
https://ncbi.nlm.nih.gov/pubmed/20504921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00286-10
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