Impaired Replication Capacity of Acute/Early Viruses in Persons Who Become HIV Controllers

Human immunodeficiency virus type 1 (HIV-1) controllers maintain viremia at <2,000 RNA copies/ml without antiretroviral therapy. Viruses from controllers with chronic infection were shown to exhibit impaired replication capacities, in part associated with escape mutations from cytotoxic-T-lymphoc...

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Hlavní autoři: Miura, Toshiyuki, Brumme, Zabrina L., Brockman, Mark A., Rosato, Pamela, Sela, Jennifer, Brumme, Chanson J., Pereyra, Florencia, Kaufmann, Daniel E., Trocha, Alicja, Block, Brian L., Daar, Eric S., Connick, Elizabeth, Jessen, Heiko, Kelleher, Anthony D., Rosenberg, Eric, Markowitz, Martin, Schafer, Kim, Vaida, Florin, Iwamoto, Aikichi, Little, Susan, Walker, Bruce D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897600/
https://ncbi.nlm.nih.gov/pubmed/20504921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00286-10
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