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PHF8 Targets Histone Methylation and RNA Polymerase II To Activate Transcription

Mutations in PHF8 are associated with X-linked mental retardation and cleft lip/cleft palate. PHF8 contains a plant homeodomain (PHD) in its N terminus and is a member of a family of JmjC domain-containing proteins. While PHDs can act as methyl lysine recognition motifs, JmjC domains can catalyze ly...

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書誌詳細
主要な著者: Fortschegger, Klaus, de Graaf, Petra, Outchkourov, Nikolay S., van Schaik, Frederik M. A., Timmers, H. T. Marc, Shiekhattar, Ramin
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897584/
https://ncbi.nlm.nih.gov/pubmed/20421419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01520-09
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