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Extracellular Signal-Regulated Kinase Promotes Rho-Dependent Focal Adhesion Formation by Suppressing p190A RhoGAP

Cell migration is critical for normal development and for pathological processes including cancer cell metastasis. Dynamic remodeling of focal adhesions and the actin cytoskeleton are crucial determinants of cell motility. The Rho family and the mitogen-activated protein kinase (MAPK) module consist...

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Autores principales: Pullikuth, Ashok K., Catling, Andrew D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897570/
https://ncbi.nlm.nih.gov/pubmed/20439493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01178-09
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