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Immunogenicity and Protection Induced by a Mycobacterium tuberculosis sigE Mutant in a BALB/c Mouse Model of Progressive Pulmonary Tuberculosis

Tuberculosis is still one of the main challenges to human global health, leading to about two million deaths every year. One of the reasons for its success is the lack of efficacy of the widely used vaccine Mycobacterium bovis BCG. In this article, we analyze the potential use of an attenuated mutan...

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Autori principali: Pando, Rogelio Hernandez, Aguilar, Leon Diana, Smith, Issar, Manganelli, Riccardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897378/
https://ncbi.nlm.nih.gov/pubmed/20457786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00023-10
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