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Prophylactic Activity of Intramuscular Peramivir in Mice Infected with a Recombinant Influenza A/WSN/33 (H1N1) Virus Containing the H274Y Neuraminidase Mutation

Peramivir is a neuraminidase (NA) inhibitor (NAI) under development that must be administered by the systemic route. The prophylactic activity of intramuscular (IM) peramivir was evaluated with mice infected with wild-type (WT) and oseltamivir-resistant (H274Y NA mutant) recombinant influenza A/WSN/...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Abed, Yacine, Simon, Philippe, Boivin, Guy
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897313/
https://ncbi.nlm.nih.gov/pubmed/20404128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01681-09
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