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HIV-1 Protease Codon 36 Polymorphisms and Differential Development of Resistance to Nelfinavir, Lopinavir, and Atazanavir in Different HIV-1 Subtypes

The amino acid at position 36 of the HIV-1 protease differs among various viral subtypes, in that methionine is usually found in subtype B viruses but isoleucine is common in other subtypes. This polymorphism is associated with higher rates of treatment failure involving protease inhibitors (PIs) in...

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Bibliographische Detailangaben
Hauptverfasser: Lisovsky, Irene, Schader, Susan M., Martinez-Cajas, Jorge-Luis, Oliveira, Maureen, Moisi, Daniela, Wainberg, Mark A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897293/
https://ncbi.nlm.nih.gov/pubmed/20404123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01828-09
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