In Vitro Hypersusceptibility of Human Immunodeficiency Virus Type 1 Subtype C Protease to Lopinavir

In order to characterize the impact of genetic polymorphisms on the susceptibility of subtype C strains of human immunodeficiency virus type 1 to protease inhibitors (PIs), a subtype B protease that originated from an infectious clone was modified through site-directed mutagenesis to include the ami...

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Autors principals: Gonzalez, Luis M. F., Brindeiro, Rodrigo M., Tarin, Michelle, Calazans, Alexandre, Soares, Marcelo A., Cassol, Sharon, Tanuri, Amilcar
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC182615/
https://ncbi.nlm.nih.gov/pubmed/12936979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.9.2817-2822.2003
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