Pharmacokinetic-Pharmacodynamic Analysis of Lopinavir-Ritonavir in Combination with Efavirenz and Two Nucleoside Reverse Transcriptase Inhibitors in Extensively Pretreated Human Immunodeficiency Virus-Infected Patients

The steady-state pharmacokinetics and pharmacodynamics of two oral doses of lopinavir-ritonavir (lopinavir/r; 400/100 and 533/133 mg) twice daily (BID) when dosed in combination with efavirenz, plus two nucleoside reverse transcriptase inhibitors, were assessed in a phase II, open-label, randomized,...

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Detalhes bibliográficos
Main Authors: Hsu, Ann, Isaacson, Jeffrey, Brun, Scott, Bernstein, Barry, Lam, Wayne, Bertz, Richard, Foit, Cheryl, Rynkiewicz, Karen, Richards, Bruce, King, Martin, Rode, Richard, Kempf, Dale J., Granneman, G. Richard, Sun, Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC148953/
https://ncbi.nlm.nih.gov/pubmed/12499212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.1.350-359.2003
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