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In Vitro Interactions between New Antitubercular Drug Candidates SQ109 and TMC207

The in vitro interactions of two new antitubercular drugs, SQ109 and TMC207, with each other and with rifampin (RIF) were evaluated. The combination of SQ109 with TMC207 (i) improved an already excellent TMC207 MIC for M. tuberculosis H37Rv by 4- to 8-fold, (ii) improved the rate of killing of bacte...

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Bibliografiske detaljer
Main Authors: Reddy, Venkata M., Einck, Leo, Andries, K., Nacy, Carol A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897281/
https://ncbi.nlm.nih.gov/pubmed/20385864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01601-09
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