Nitazoxanide Inhibits Biofilm Formation by Staphylococcus epidermidis by Blocking Accumulation on Surfaces

Coagulase-negative species of Staphylococcus are often associated with opportunistic hospital-acquired infections that arise from the colonization of indwelling catheters. Here we show that the antiparasitic drug nitazoxanide (NTZ) and its active metabolite, tizoxanide (TIZ), are inhibitory to the g...

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Bibliographic Details
Main Authors: Tchouaffi-Nana, Florence, Ballard, T. Eric, Cary, Christine H., Macdonald, Timothy L., Sifri, Costi D., Hoffman, Paul S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
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Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897279/
https://ncbi.nlm.nih.gov/pubmed/20404119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00901-09
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