Functional T-Cell Deficiency in Adolescents Who Experience Serogroup C Meningococcal Disease despite Receiving the Meningococcal Serogroup C Conjugate Vaccine

Some individuals have experienced meningococcal disease despite receiving the meningococcal serogroup C conjugate (MCC) vaccine in adolescence. We sought to determine whether this is due to subclinical functional B- or T-cell immunodeficiency. Of 53 vaccine failures identified by enhanced surveillan...

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Main Authors: Foster, Rachel A., Carlring, Jennifer, Lees, Andrew, Borrow, Ray, Ramsay, Mary, Kacsmarski, Ed, Miller, Elizabeth, McKendrick, Michael W., Heath, Andrew W., Read, Robert C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Vaccine Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897263/
https://ncbi.nlm.nih.gov/pubmed/20463106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00481-09
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