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Evidence of a Functional B-Cell Immunodeficiency in Adults Who Experience Serogroup C Meningococcal Disease

After adolescence, the incidence of meningococcal disease decreases with age as a result of the cumulative immunizing effect of repeated nasopharyngeal colonization. Nevertheless, some adults succumb to meningococcal disease, so we hypothesized that this is due to a subtle functional immunological d...

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Detalhes bibliográficos
Main Authors: Foster, Rachel A., Carlring, Jennifer, McKendrick, Michael W., Lees, Andrew, Borrow, Ray, Read, Robert C., Heath, Andrew W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681599/
https://ncbi.nlm.nih.gov/pubmed/19279166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00485-08
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