Strong HIV-Specific CD4(+) and CD8(+) T-Lymphocyte Proliferative Responses in Healthy Individuals Immunized with an HIV-1 DNA Vaccine and Boosted with Recombinant Modified Vaccinia Virus Ankara Expressing HIV-1 Genes

We investigated HIV-1 vaccine-induced lymphoproliferative responses in healthy volunteers immunized intradermally or intramuscularly (with or without adjuvant granulocyte-macrophage colony-stimulating factor [GM-CSF] protein) with DNA expressing HIV-1 gag, env, rev, and rt at months 0, 1, and 3 usin...

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Main Authors: Aboud, Said, Nilsson, Charlotta, Karlén, Katarina, Marovich, Mary, Wahren, Britta, Sandström, Eric, Gaines, Hans, Biberfeld, Gunnel, Godoy-Ramirez, Karina
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccine Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897257/
https://ncbi.nlm.nih.gov/pubmed/20463104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00008-10
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