α-Synuclein sequesters arachidonic acid to modulate SNARE-mediated exocytosis

α-Synuclein is a synaptic modulatory protein implicated in the pathogenesis of Parkinson disease. The precise functions of this small cytosolic protein are still under investigation. α-Synuclein has been proposed to regulate soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNAR...

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Autores principales: Darios, Frédéric, Ruipérez, Violeta, López, Inmaculada, Villanueva, Jose, Gutierrez, Luis M, Davletov, Bazbek
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2010
Materias:
Scientific Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897113/
https://ncbi.nlm.nih.gov/pubmed/20489724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.66
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