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Mechanism of arachidonic acid action on syntaxin–Munc18

Syntaxin and Munc18 are, in tandem, essential for exocytosis in all eukaryotes. Recently, it was shown that Munc18 inhibition of neuronal syntaxin 1 can be overcome by arachidonic acid, indicating that this common second messenger acts to disrupt the syntaxin–Munc18 interaction. Here, we show that a...

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Detalles Bibliográficos
Main Authors: Connell, Emma, Darios, Frédéric, Broersen, Kerensa, Gatsby, Naomi, Peak-Chew, Sew-Yeu, Rickman, Colin, Davletov, Bazbek
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852766/
https://ncbi.nlm.nih.gov/pubmed/17363971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400935
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