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Conserved Discrimination Against Misacylated tRNAs by Two Mesophilic Elongation Factor Tu Orthologs
Elongation Factor Tu (EF-Tu) binds and loads elongating aminoacyl-transfer RNAs (aa-tRNAs) onto the ribosome for protein biosynthesis. Many bacteria biosynthesize Gln-tRNA(Gln) and Asn-tRNA(Asn) by an indirect, two-step pathway that relies on the misacylated tRNAs Glu-tRNA(Gln) and Asp-tRNA(Asn) as...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2897013/ https://ncbi.nlm.nih.gov/pubmed/18627126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800369q |
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