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Conserved Discrimination Against Misacylated tRNAs by Two Mesophilic Elongation Factor Tu Orthologs

Elongation Factor Tu (EF-Tu) binds and loads elongating aminoacyl-transfer RNAs (aa-tRNAs) onto the ribosome for protein biosynthesis. Many bacteria biosynthesize Gln-tRNA(Gln) and Asn-tRNA(Asn) by an indirect, two-step pathway that relies on the misacylated tRNAs Glu-tRNA(Gln) and Asp-tRNA(Asn) as...

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Detalhes bibliográficos
Main Authors: Cathopoulis, Terry J. T., Chuawong, Pitak, Hendrickson, Tamara L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897013/
https://ncbi.nlm.nih.gov/pubmed/18627126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800369q
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