The maturation of GABAergic transmission in visual cortex requires endocannabinoid-mediated LTD of inhibitory inputs during a critical period

Endocannabinoids are widely regarded as negative modulators of presynaptic release. Here we present evidence that in visual cortex endocannabinoids are crucial for the maturation of GABAergic release. We found that between eye opening and puberty, release changes from an immature state with high rel...

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Main Authors: Jiang, Bin, Huang, Shiyong, de Pasquale, Roberto, Millman, Daniel, Song, Lihua, Lee, Hey-Kyoung, Tsumoto, Tadaharu, Kirkwood, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897012/
https://ncbi.nlm.nih.gov/pubmed/20435001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.03.021
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