The maturation of GABAergic transmission in visual cortex requires endocannabinoid-mediated LTD of inhibitory inputs during a critical period

Endocannabinoids are widely regarded as negative modulators of presynaptic release. Here we present evidence that in visual cortex endocannabinoids are crucial for the maturation of GABAergic release. We found that between eye opening and puberty, release changes from an immature state with high rel...

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Bibliografiske detaljer
Main Authors: Jiang, Bin, Huang, Shiyong, de Pasquale, Roberto, Millman, Daniel, Song, Lihua, Lee, Hey-Kyoung, Tsumoto, Tadaharu, Kirkwood, Alfredo
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897012/
https://ncbi.nlm.nih.gov/pubmed/20435001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.03.021
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