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The IL-2 Defect in Systemic Lupus Erythematosus Disease Has an Expansive Effect on Host Immunity

IL-2 production is decreased in systemic lupus erythematosus (SLE) patients and affects T cell function and other aspects of host immunity. Transcription factors regulating IL-2 production behave aberrantly in SLE T cells. In addition to IL-2 dysregulation, other IL-2 family members (IL-15 and IL-21...

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Detalhes bibliográficos
Main Authors: Lieberman, Linda A., Tsokos, George C.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896881/
https://ncbi.nlm.nih.gov/pubmed/20625413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/740619
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