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The IL-2 Defect in Systemic Lupus Erythematosus Disease Has an Expansive Effect on Host Immunity
IL-2 production is decreased in systemic lupus erythematosus (SLE) patients and affects T cell function and other aspects of host immunity. Transcription factors regulating IL-2 production behave aberrantly in SLE T cells. In addition to IL-2 dysregulation, other IL-2 family members (IL-15 and IL-21...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Hindawi Publishing Corporation
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896881/ https://ncbi.nlm.nih.gov/pubmed/20625413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/740619 |
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