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Impairment of pre-mRNA splicing in liver disease: Mechanisms and consequences

Pre-mRNA splicing is an essential step in the process of gene expression in eukaryotes and consists of the removal of introns and the linking of exons to generate mature mRNAs. This is a highly regulated mechanism that allows the alternative usage of exons, the retention of intronic sequences and th...

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Detalhes bibliográficos
Main Authors: Berasain, Carmen, Goñi, Saioa, Castillo, Josefa, Latasa, María Ujue, Prieto, Jesús, Ávila, Matías A
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896746/
https://ncbi.nlm.nih.gov/pubmed/20593494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i25.3091
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