Hippocampal NPY gene transfer attenuates seizures without affecting epilepsy-induced impairment of LTP

Recently, hippocampal neuropeptide Y (NPY) gene therapy has been shown to effectively suppress both acute and chronic seizures in animal model of epilepsy, thus representing a promising novel antiepileptic treatment strategy, particularly for patients with intractable mesial temporal lobe epilepsy (...

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Bibliographic Details
Main Authors: Sørensen, Andreas T., Nikitidou, Litsa, Ledri, Marco, Lin, En-Ju D., During, Matthew J., Kanter-Schlifke, Irene, Kokaia, Merab
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896682/
https://ncbi.nlm.nih.gov/pubmed/19038255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2008.10.015
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