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Effects of SREBF-1a and SCAP polymorphisms on plasma levels of lipids, severity, progression and regression of coronary atherosclerosis and response to therapy with fluvastatin

Sterol regulatory elements binding factor-1a (SREBF-1a) and SREBF cleavage activating protein (SCAP) regulate lipids homeostasis. Polymorphisms in SREBF-1a and SCAP could affect plasma levels of lipids and risk of atherosclerosis. We determined association of SREBF-1a −36del/G and SCAP 2386A/G genot...

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Autors principals: Salek, Lorraine, Lutucuta, Silvia, Ballantyne, Christie M., Gotto, Antonio M., Marian, A.J.
Format: Artigo
Idioma:Inglês
Publicat: 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896566/
https://ncbi.nlm.nih.gov/pubmed/12436350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-002-0381-z
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