A Common PCSK9 Haplotype, Encompassing the E670G Coding Single Nucleotide Polymorphism, Is a Novel Genetic Marker for Plasma Low-Density Lipoprotein Cholesterol Levels and Severity of Coronary Atherosclerosis

OBJECTIVES: We sought to determine the effects of PCSK9 variants on plasma low-density lipoprotein cholesterol (LDL-C) levels, severity of coronary atherosclerosis, and response to statin therapy in the Lipoprotein Coronary Atherosclerosis Study (LCAS) population. BACKGROUND: Mutations in PCSK9 caus...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chen, Suet N., Ballantyne, Christie M., Gotto, Antonio M., Tan, Yanli, Willerson, James T., Marian, Ali J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910256/
https://ncbi.nlm.nih.gov/pubmed/15893176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2005.01.051
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados