Quantitative detection of 4-hydroxyequilenin–DNA adducts in mammalian cells using an immunoassay with a novel monoclonal antibody

Estrogen–DNA adducts are potential biomarkers for assessing the risk and development of estrogen-associated cancers. 4-Hydroxyequilenin (4-OHEN) and 4-hydroxyequilin (4-OHEQ), the metabolites of equine estrogens present in common hormone replacement therapy (HRT) formulations, are capable of produci...

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Autors principals: Okahashi, Yumiko, Iwamoto, Takaaki, Suzuki, Naomi, Shibutani, Shinya, Sugiura, Shigeki, Itoh, Shinji, Nishiwaki, Tomohisa, Ueno, Satoshi, Mori, Toshio
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Methods Online
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896538/
https://ncbi.nlm.nih.gov/pubmed/20406772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq233
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