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Less Carcinogenic Chlorinated Estrogens Applicable to Hormone Replacement Therapy

Human estrogens prescribed for hormone replacement therapy (HRT) are known to be potent carcinogens. To find safer estrogens, several chlorinated estrogens were synthesized and their carcinogenic potential were determined. A pellet containing either 2-chloro-17β-estradiol (2-ClE(2)) or 4-chloro-17β-...

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Publicado en:Int J Mol Sci
Main Authors: Okamoto, Yoshinori, Jinno, Hideto, Itoh, Shinji, Shibutani, Shinya
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268473/
https://ncbi.nlm.nih.gov/pubmed/34281275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22137222
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