Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m(7)G methyltransferases

Sgm (Sisomicin-gentamicin methyltransferase) from antibiotic-producing bacterium Micromonospora zionensis is an enzyme that confers resistance to aminoglycosides like gentamicin and sisomicin by specifically methylating G1405 in bacterial 16S rRNA. Sgm belongs to the aminoglycoside resistance methyl...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Husain, Nilofer, Tkaczuk, Karolina L., Tulsidas, Shenoy Rajesh, Kaminska, Katarzyna H., Čubrilo, Sonja, Maravić-Vlahoviček, Gordana, Bujnicki, Janusz M., Sivaraman, J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2010
Aiheet:
Structural Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896518/
https://ncbi.nlm.nih.gov/pubmed/20194115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq122
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