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Identification of a structural element of the hepatitis C virus minus strand RNA involved in the initiation of RNA synthesis
The replication of the genomic RNA of the hepatitis C virus (HCV) of positive polarity involves the synthesis of a replication intermediate of negative polarity by the viral RNA-dependent RNA polymerase (NS5B). In vitro and likely in vivo, the NS5B initiates RNA synthesis without primers. This de no...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896513/ https://ncbi.nlm.nih.gov/pubmed/20194114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq109 |
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