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Evolution of Metal Selectivity in Templated Protein Interfaces

Selective binding by metalloproteins to their cognate metal ions is essential to cellular survival. How proteins originally acquired the ability to selectively bind metals and evolved a diverse array of metal-centered functions despite the availability of only a few metal-coordinating functionalitie...

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Main Authors: Brodin, Jeffrey D., Medina-Morales, Annette, Ni, Thomas, Salgado, Eric N., Ambroggio, Xavier I., Tezcan, F. Akif
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896502/
https://ncbi.nlm.nih.gov/pubmed/20515031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja910844n
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