Attenuated mTOR Signaling and Enhanced Autophagy in Adipocytes from Obese Patients with Type 2 Diabetes

Type 2 diabetes (T2D) is strongly linked to obesity and an adipose tissue unresponsive to insulin. The insulin resistance is due to defective insulin signaling, but details remain largely unknown. We examined insulin signaling in adipocytes from T2D patients, and contrary to findings in animal studi...

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Detalhes bibliográficos
Main Authors: Öst, Anita, Svensson, Kristoffer, Ruishalme, Iida, Brännmark, Cecilia, Franck, Niclas, Krook, Hans, Sandström, Per, Kjolhede, Preben, Strålfors, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896460/
https://ncbi.nlm.nih.gov/pubmed/20386866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2010.00023
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