Attenuated mTOR Signaling and Enhanced Autophagy in Adipocytes from Obese Patients with Type 2 Diabetes

Type 2 diabetes (T2D) is strongly linked to obesity and an adipose tissue unresponsive to insulin. The insulin resistance is due to defective insulin signaling, but details remain largely unknown. We examined insulin signaling in adipocytes from T2D patients, and contrary to findings in animal studi...

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Hlavní autoři: Öst, Anita, Svensson, Kristoffer, Ruishalme, Iida, Brännmark, Cecilia, Franck, Niclas, Krook, Hans, Sandström, Per, Kjolhede, Preben, Strålfors, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: ScholarOne 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896460/
https://ncbi.nlm.nih.gov/pubmed/20386866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2010.00023
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