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Detection of susceptibility genes as modifiers due to subgroup differences in complex disease

Complex diseases invariably involve multiple genes and often exhibit variable symptom profiles. The extent to which disease symptoms, course, and severity differ between affected individuals may result from underlying genetic heterogeneity. Genes with modifier effects may or may not also influence d...

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Main Authors: Bergen, Sarah E, Maher, Brion S, Fanous, Ayman H, Kendler, Kenneth S
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896458/
https://ncbi.nlm.nih.gov/pubmed/20354561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.39
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