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Detection of susceptibility genes as modifiers due to subgroup differences in complex disease
Complex diseases invariably involve multiple genes and often exhibit variable symptom profiles. The extent to which disease symptoms, course, and severity differ between affected individuals may result from underlying genetic heterogeneity. Genes with modifier effects may or may not also influence d...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896458/ https://ncbi.nlm.nih.gov/pubmed/20354561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.39 |
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