Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-β2 and Ran-GTP

The biogenesis, maintenance, and function of primary cilia are controlled through intraflagellar transport (IFT) driven by two kinesin-2 family members, the heterotrimeric KIF3A/KIF3B/KAP complex and the homodimeric KIF17 motor1,2. How these motors and their cargoes gain access to the ciliary compar...

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Autori principali: Dishinger, John F., Kee, Hooi Lynn, Jenkins, Paul M., Fan, Shuling, Hurd, Toby W., Hammond, Jennetta W., Truong, Yen Nhu-Thi, Margolis, Ben, Martens, Jeffrey R., Verhey, Kristen J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896429/
https://ncbi.nlm.nih.gov/pubmed/20526328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2073
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