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Localization of retinitis pigmentosa 2 to cilia is regulated by Importin β2

Ciliopathies represent a newly emerging group of human diseases that share a common etiology resulting from dysfunction of the cilium or centrosome. The gene encoding the retinitis pigmentosa 2 protein (RP2) is mutated in X-linked retinitis pigmentosa. RP2 localizes to the ciliary base and this requ...

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Bibliografske podrobnosti
Main Authors: Hurd, Toby W., Fan, Shuling, Margolis, Ben L.
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039017/
https://ncbi.nlm.nih.gov/pubmed/21285245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.070839
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