טוען...
Formal synthesis of salinosporamide A via NHC-catalyzed intramolecular lactonization
An N-heterocyclic carbene (NHC) catalyzed intramolecular lactonization to prepare densely functionalized bicyclic γ-lactam-γ-lactone adducts from enals is reported. This method has been applied to the formal synthesis of salinosporamide A, a potent 20S proteasome inhibitor and anti-cancer therapeuti...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2009
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896295/ https://ncbi.nlm.nih.gov/pubmed/20606761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2009.03.103 |
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