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Effect of Heparin Oligomer Chain Length on the Activation of Valvular Interstitial Cells

A key event in connective tissue remodeling involves the transformation of fibroblasts to myofibroblasts, also revealed by expression of α-smooth muscle actin (α-SMA). However, misregulation of this transition can lead to fibrosis, an overgrowth and hardening of tissue due to excess extracellular ma...

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Detalhes bibliográficos
Main Authors: Pedron, Sara, Kasko, Andrea M., Peinado, Carmen, Anseth, Kristi S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896009/
https://ncbi.nlm.nih.gov/pubmed/20446725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm100211k
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