Directed differentiation of human induced pluripotent stem cells generates active motor neurons

The potential for directed differentiation of human induced pluripotent stem (iPS) cells to functional post-mitotic neuronal phenotypes is unknown. Following methods shown to be effective at generating motor neurons from human embryonic stem cells (hESCs), we found that once specified to a neural li...

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Detalhes bibliográficos
Main Authors: Karumbayaram, S, Novitch, BG, Patterson, M, Umbach, JA, Richter, L, Lindgren, A, Conway, A, Clark, A, Goldman, SA, Plath, K, Wiedau-Pazos, M, Kornblum, HI, Lowry, WE
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895909/
https://ncbi.nlm.nih.gov/pubmed/19350680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.31
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