Pathogen-Mediated Inflammatory Atherosclerosis Is Mediated in Part via Toll-Like Receptor 2-Induced Inflammatory Responses

Studies in humans have established that polymorphisms in genes encoding the innate immune Toll-like receptors (TLRs) are associated with inflammatory atherosclerosis. In hyperlipidemic mice, TLR2 and TLR4 have been reported to contribute to atherosclerosis progression. Human and mouse studies suppor...

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Main Authors: Hayashi, Chie, Madrigal, Andres G., Liu, Xinyan, Ukai, Takashi, Goswami, Sulip, Gudino, Cynthia V., Gibson, III, Frank C., Genco, Caroline A.
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895755/
https://ncbi.nlm.nih.gov/pubmed/20505314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000314686
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