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Macrophage-Elicited Osteoclastogenesis in Response to Bacterial Stimulation Requires Toll-Like Receptor 2-Dependent Tumor Necrosis Factor-Alpha Production

The receptor activator of NF-κB ligand (RANKL) and the proinflammatory cytokines are believed to play important roles in osteoclastogenesis. We recently reported that the innate immune recognition receptor, Toll-like receptor 2 (TLR2), is crucial for inflammatory bone loss in response to infection b...

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Detalhes bibliográficos
Main Authors: Ukai, Takashi, Yumoto, Hiromichi, Gibson, Frank C., Genco, Caroline Attardo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223461/
https://ncbi.nlm.nih.gov/pubmed/17998311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01241-07
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