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Restriction of Receptor Movement Alters Cellular Response: Physical Force Sensing by EphA2
Activation of the EphA2 receptor tyrosine kinase by ephrin-A1 ligands presented on apposed cell surfaces plays important roles in development and exhibits poorly understood functional alterations in cancer. We reconstituted this intermembrane signaling geometry between live EphA2-expressing human br...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895569/ https://ncbi.nlm.nih.gov/pubmed/20223987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1181729 |
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