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Desensitization of vascular response in vivo: Contribution of genetic variation in the alpha(2B)-adrenergic receptor subtype
OBJECTIVES: Vascular alpha(2B) adrenergic receptors (α(2B)-ARs) mediate vasoconstriction and contribute to peripheral regulation of vascular tone. In vitro, a common 301-303 deletion in the α(2B)-AR gene, ADRA2B, results in loss of α(2B)-AR desensitization. We examined the hypothesis that ADRA2B del...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895551/ https://ncbi.nlm.nih.gov/pubmed/20051907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e328333d212 |
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