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Enzymatic Total Synthesis of Rabelomycin, an Angucycline Group Antibiotic

[Image: see text] A one-pot enzymatic total synthesis of angucycline antibiotic rabelomycin was accomplished, starting from acetyl-CoA and malonyl-CoA, using a mixture of polyketide synthase (PKS) enzymes of the gilvocarcin, ravidomycin, and jadomycin biosynthetic pathways. The in vitro results were...

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Sonraí Bibleagrafaíochta
Main Authors: Kharel, Madan Kumar, Pahari, Pallab, Lian, Hui, Rohr, Jürgen
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895501/
https://ncbi.nlm.nih.gov/pubmed/20486694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol1009009
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