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Enzymatic Total Synthesis of Rabelomycin, an Angucycline Group Antibiotic
[Image: see text] A one-pot enzymatic total synthesis of angucycline antibiotic rabelomycin was accomplished, starting from acetyl-CoA and malonyl-CoA, using a mixture of polyketide synthase (PKS) enzymes of the gilvocarcin, ravidomycin, and jadomycin biosynthetic pathways. The in vitro results were...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895501/ https://ncbi.nlm.nih.gov/pubmed/20486694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol1009009 |
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