Immunization of Guinea Pigs with Novel Hepatitis B Antigen as Nanoparticle Aggregate Powders Administered by the Pulmonary Route

Novel nanoparticle-aggregate formulations containing recombinant hepatitis B surface antigen (rHBsAg) were administered to the lungs of guinea pigs and antibodies generated to this antigen evaluated. Preparations of dry powders of: (a) rHBsAg encapsulated within poly(lactic-co-glycolic acid) (PLGA)/...

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Hlavní autoři: Muttil, Pavan, Prego, Cecilia, Garcia-Contreras, Lucila, Pulliam, Brian, Fallon, John Kevin, Wang, Chenchen, Hickey, Anthony James, Edwards, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2010
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895445/
https://ncbi.nlm.nih.gov/pubmed/20419360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9192-2
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