Combinatorial Cysteine Mutagenesis Reveals a Critical Intramonomer Role for Cysteines in Prestin Voltage Sensing

Prestin is a member of the SLC26 family of anion transporters and is responsible for electromotility in outer hair cells, the basis of cochlear amplification in mammals. It is an anion transporting transmembrane protein, possessing nine cysteine residues, which generates voltage-dependent charge mov...

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Detaylı Bibliyografya
Asıl Yazarlar: Bai, Jun-Ping, Surguchev, Alexei, Bian, Shumin, Song, Lei, Santos-Sacchi, Joseph, Navaratnam, Dhasakumar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2010
Konular:
Cellular Biophysics and Electrophysiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895379/
https://ncbi.nlm.nih.gov/pubmed/20655836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.066
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