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Exogenous thioredoxin prevents ethanol-induced oxidative damage and apoptosis in mouse liver

Ethanol-induced liver injury is characterized by increased formation of reactive oxygen species (ROS) and inflammatory cytokines, resulting in the development of hepatic steatosis, injury and cell death by necrosis and apoptosis. Thioredoxin (Trx), a potent antioxidant and anti-inflammatory molecule...

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Autors principals: Cohen, Jessica I., Roychowdhury, Sanjoy, DiBello, Patricia M., Jacobsen, Donald W., Nagy, Laura E.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895317/
https://ncbi.nlm.nih.gov/pubmed/19205032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22837
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