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Exogenous thioredoxin prevents ethanol-induced oxidative damage and apoptosis in mouse liver

Ethanol-induced liver injury is characterized by increased formation of reactive oxygen species (ROS) and inflammatory cytokines, resulting in the development of hepatic steatosis, injury and cell death by necrosis and apoptosis. Thioredoxin (Trx), a potent antioxidant and anti-inflammatory molecule...

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Detalhes bibliográficos
Main Authors: Cohen, Jessica I., Roychowdhury, Sanjoy, DiBello, Patricia M., Jacobsen, Donald W., Nagy, Laura E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895317/
https://ncbi.nlm.nih.gov/pubmed/19205032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22837
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